It was revealed that Whole-body cryotherapy induced relaxation, mood elevation, memory enhancement, an improvement in vigor, a significant decrease in tension and fatigue, and a boost in energy levels (Rymaszewska, Bialy, Zagrobelny, & Kiejna, 2000).

 

Such benefits are related to the influence of whole-body cryotherapy on the hypothalamic-pituitary axis (HPA) and monoamine regulation, increased β-endorphin levels, hippocampal brain-derived neurotrophic factor (BDNF) normalization, and improved perceptions of self efficacy (Rymaszewska, Ramsey, & Chładzińska-Kiejna, 2008).

 

Another problem that arises due to anxiety, depression, stress, and intake of substances such as caffeine and nicotine, is a condition called insomnia (difficulty in falling asleep).(Mayo Clinic, 2014). Monoamine neurotransmitters, particularly serotonin, play a major role in the regulation of the sleep-wake cycle. When imbalanced, will result in the disruption of sleep (Hurd, 2011). As shown in the study conducted by Rymaszewska, Ramsey, & Chładzińska-Kiejna, 2008, whole-body cryotherapy helps promote sleep among patients with insomnia through the regulation of monoamine neurotransmitters.